On the other hand, reports have depicted that positively billed NPs possess bigger affinity to negatively charged pores and skin pores, when applied on untreated skin. Therefore, the authors coated MB@MSNs with positively charged poly-L-lysine (PLL) and further confirmed the demand with zeta opportu

The structure with the unliganded double mutant HIV-one RT showed that Lys103Asn mutation facilitates coordination of the sodium ion with Lys101 O, Asn103 N and O(delta1), Tyr188 O(eta), and two h2o molecules. The formation on the binding pocket demands the elimination on the sodium ion. Although th